Report Overview
Product Overview
Downstream Processing Market size was USD 22.94 billion in 2021 and projected to grow from USD 29.7 billion in 2023 to USD 96.9 billion by 2032, exhibiting a CAGR of 14.0% during the forecast period.
Downstream processing is the purification and recovery of biosynthetic products, mainly the pharmaceuticals from natural sources like plant or animal tissue or fermentation, both comprising the disposal and proper treatment of waste and recycling of salvageable elements. This process separates, purifies, and isolates products from (RDT). This is a critical stage in the production of medicines, industrial enzymes, and flavor chemicals and natural fragrance.
Market Highlights
Downstream Processing Market is expected to project a CAGR of 14.0% during the forecast period, 2022-2032
Downstream Processing Market is expected to reach USD 96.9 billion, growing at a CAGR of 14.0% during the forecast period owing to the rising pharmaceutical expenditure on R&D, improved technology, and implementation of multiple business strategies. This enables the biopharmaceutical business to adopt downstream processing on a larger scale. These are the key factors expected to boost the growth of downstream Processing Market over the forecast period
Downstream Processing Market Segmentation
Chromatography Systems segment is expected to dominate in the forecast period
Downstream Processing Market is classified based on the Product into Chromatography Systems, Filters, Evaporators, Centrifuges, Dryers, and Others. The Chromatography segment conquered maximum share of the market in 2022 and is projected to lead in future as well. Many firms provide secure and integrated systems that function effectively throughout the demanding stages of process development and production scale. Technological advancements led to the growth of single-use chromatography, regarded a bright invention in the biopharmaceutical sector and is expected to witness positive growth throughout the projection period.
Antibodies Production segment is expected to dominate in the forecast period
Downstream Processing Market is classified based on the Application into Antibiotic Production, Hormone Production, Antibodies Production, Enzyme Production, and Vaccine Production. The Antibiotic Production segment held major share in 2022 and generated the maximum revenue due to broad applications of antibiotics for treating multiple disorders. The Antibodies Production segment is predicted to develop at the quickest CAGR by 2030, owing to increased monoclonal antibodies demand and the launch of novel products for effective antibody purification.
Market Dynamics
Growth Drivers
Rising Adoption of Biotech Process in Different Industries is Expected to Boost the Market Growth
Rising demand for bioproducts, increasing adoption of biotech procedures in the pharmaceutical, agricultural, and bio-services industries, increasing adoption of single-use technology in bioprocessing, and rapid advancements in gene therapy and genetic engineering are driving market growth. Furthermore, the increased commercial progress made by biopharma businesses is fuelling market growth. Furthermore, as key biopharmaceutical patents expire, new prospects for downstream processing companies will emerge throughout the projected period.
Growing Research and Development to Modernize Bioprocess Technologies is Expected to Boost the Market Growth
The application of constant downstream processing instruments for multicomponent separations, high-throughput procedure development, perfusion chromatography instruments, and membrane systems (high-resolution) has come from an increase in R&D activities relevant to advanced bioprocess technologies. Hence, there is a greater demand for improved bioprocessing technology to solve the purifying bottleneck. This is projected to propel the growth of the Downstream Processing Market.
Restraint
Significantly Priced Instruments and Need for Skilled Experts May Restrain the Market Growth
The high cost of instruments and the shortage of experienced personnel are projected to limit the expansion of the market during the forecast period. Furthermore, the primary hurdles in Downstream Processing Market are a purification bottleneck, a shortage of single-use solutions, and lack of experienced specialists.
Recent Developments
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Thermo Fisher Scientific to open a bioprocessing manufacturing center in Ogden, Utah, in April 2022, for the progress of vaccines and biologics.
- Sartorius began focusing on the expansion of its global production capacity in May 2022, with the growth of its manufacturing location in Tunisia.
Downstream Processing Market
Key Players Covered:
- 3M Company
- Corning Corporation
- Asahi Kasei
- Dover Corporation
- Merck Millipore
- Lonza Group Ltd
- Mettler Toledo
- Sartorius Stedim Biotech S.A
- Cytiva
- BioXcellence
- Eppendorf AG
- BioPharm International
- Repligen
- Finesse Solutions Inc.
- Other Prominent Players (Company Overview, Business Strategy, Key Product Offerings, Financial Performance, Key Performance Indicators, Risk Analysis, Recent Development, Regional Presence, SWOT Analysis)
Regional Analysis
Downstream Processing Market is segmented based on regional analysis into five major regions: North America, Latin America, Europe, Asia Pacific and the Middle East and Africa. North America registered the greater market share in 2022 and is expected to continue its strong grip throughout the forecast period. This expanding industry is propelled by rising demand for biopharmaceuticals and escalating R&D expenditure in the biopharmaceutical industry. Since various nations like China, India, South Korea, and Japan are expected to boost the demand for downstream processing products in the next years, the Asia Pacific area is projected to hold major growth during the estimated period.
Impact of Covid-19 on Downstream Processing Market
Several industries were forced to close due to the COVID-19 epidemic. Social distancing rules and limitations on travel are hampering commodities into warehouses, limiting the growth of the Downstream Processing Market. The growth of the Downstream Processing Market was hindered during the Covid-9 epidemic due to its reliance on real estate operations. Construction sites had been closed, and Covid-19 had a negative influence on the Downstream Processing Market.
Downstream Processing Market is further segmented by region into:
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North America Market Size, Share, Trends, Opportunities, Y-o-Y Growth, CAGR – United States and Canada
- Latin America Market Size, Share, Trends, Opportunities, Y-o-Y Growth, CAGR – Mexico, Argentina, Brazil, and Rest of Latin America
- Europe Market Size, Share, Trends, Opportunities, Y-o-Y Growth, CAGR – United Kingdom, France, Germany, Italy, Spain, Belgium, Hungary, Luxembourg, Netherlands, Poland, NORDIC, Russia, Turkey, and Rest of Europe
- Asia Pacific Market Size, Share, Trends, Opportunities, Y-o-Y Growth, CAGR – India, China, South Korea, Japan, Malaysia, Indonesia, New Zealand, Australia, and Rest of APAC
- Middle East and Africa Market Size, Share, Trends, Opportunities, Y-o-Y Growth, CAGR – North Africa, Israel, GCC, South Africa, and Rest of MENA
Downstream Processing Market Scope and Segments:
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ATTRIBUTE |
DETAILS |
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Study Period |
2018-2032 |
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Base Year |
2022 |
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Forecast Period |
2022-2032 |
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Historical Period |
2019-2021 |
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Growth Rate |
CAGR of 14.0% from 2022-2032 |
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Unit |
Value (USD Billion) |
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Segmentation |
Main Segments List |
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Product |
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Technique |
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Application |
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By Region |
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Frequently Asked Questions (FAQ):
Downstream Processing Market size was estimated at USD 22.94 billion in 2021 and is expected to reach USD 96.9 billion in 2032.
Downstream processing is the purification and recovery of biosynthetic products, mainly the pharmaceuticals from natural sources like plant or animal tissue or fermentation, both comprising the disposal and proper treatment of waste and recycling of salvageable elements.
Chromatography Systems and Antibodies Production segments accounted for the largest Downstream Processing Market share.
Key players: Thermo Fisher Scientific Inc., 3M Company, Corning Corporation, Asahi Kasei, Dover Corporation, Merck Millipore, Lonza Group Ltd, Mettler Toledo, Sartorius Stedim Biotech S.A, Cytiva, BioXcellence, Eppendorf AG, BioPharm International, Repligen, Finesse Solutions Inc., and Other Prominent Players are the key players in the Downstream Processing Market.
Expansion of the biotechnology sector on the global scale and growing R&D investment in the biopharmaceutical sector are the factors driving the Downstream Processing Market.
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